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Ongoing Projects

1

Metabolomic profile in TB

The aim of this study is to characterize the specific urinary metabolome released from TB patients by nuclear magnetic resonance in order to be used for diagnostic purposes.

3

Performance of a new generation IGRA in immunocompromised individuals

This study is designed to evaluate the performance of this new ELISA based QuantiFERON-TB plus In-tube test in immunosuppressed populations.

5

Migrant-sensitive care and tuberculosis treatment outcome and completion

The aim of the study is to assess whether migrant-sensitive care strategies lead to an increase of successful active TB and LTBI treatment outcomes in migrants.

7

Cost of TB drugs and the availability of drug susceptibility testing for new TB drugs

Two TBnet studies to evaluate cost of TB drugs as well as their availability.

A prospective descriptive cross-sectional observational study

Tuberculosis Screening in Ukrainian Refugees: Countries practices

9

2

Management of tuberculosis in transplant recipients

This multicentric retrospective cohort study will compare the incidence of tuberculosis at least two years after transplant in those with screening and those without screening.

4

Clinical Evaluation of miniMDR-TB® test kit

This study aims to assess the clinical impact of the miniMDR-TB test for the diagnosis of multidrug-resistant tuberculosis.

6

Safety and effectiveness of the coadministration of direct-acting antivirals for HCV and MDR-TB treatment

The main objective of the study is to assess the safety and effectiveness of concomitant treatment for chronic HCV infection and for MDR-TB.

Pragmatic trial on safety and tolerability of an optimized (high) dose of rifampicin in tuberculosis patients’

Pragmatic Optimized
Rifampicin Trial (PORT)

8

Xpert MTB/RIF false positive results in patients with tuberculosis

10

risk factors and impact on clinical outcome

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